your son probably has an FM modulator for his Ipod which is hooked up in between the stereo and the antenna coaxial cable. This takes the signal and directly inputs it into the antenna input on the stereo. This is different then the FM Transmitters you can buy which sends a small power signal to the antenna a few feet away. The modulator just skips this step.
Your rear defrost, I suspect, is interfering with the FM antenna (also in the back window) due to a partial ground somewhere along the defroster wires. This excess noise/static is so small but so close to the antenna that you hear it in the radio.
I had something similar in my guitar amplifier. Some times I would have an annoying hum (static) and if I touched something that was grounded it would go away. Its weird but thats how electronics work sometimes. I don't think you will be able to find an affordable solution (replace back window, or press the defrost button twice!?!), just live with the gremlins in your radio.
